The MRI compatible rat and mouse monitor is a device specially developed by Starr Company for vital sign detection of rats and mice in MRI magnetic resonance environment.

It is possible to non invasively measure the blood oxygen saturation, pulse rate, respiratory rate, pulse amplitude, and respiratory amplitude of small animals (such as mice, rats, guinea pigs, rabbits, etc.) in an MRI environment;

All measurements are taken through a non-invasive sensor;

Main functions:

·Non magnetic probe, suitable for monitoring vital signs of animals in nuclear magnetic environment;

·Monitor and record various cardiopulmonary function parameters: arterial oxygen saturation, pulse, pulse amplitude, respiratory rate, respiratory amplitude

·Can output simulated data

All measurements are completed through a non-invasive sensor, which is accurate, convenient, and efficient.

Model: MouseOx is currently testing mice under anesthesia

There are multiple probes to choose from:

·According to experimental requirements: rat type probe and mouse type probe can be selected;

·According to the animal's state: the probe can be selected for continuous measurement of conscious activity state and anesthesia (or surgery) state measurement;

·According to the number of animals: there are multi-channel adapters to choose from, which can simultaneously detect the vital signs of multiple animals;

·According to the usage environment: non-magnetic probes suitable for nuclear magnetic environments can be selected;

Verified accuracy:

The comparison between invasive blood gas sampling measurement results and non-invasive MouseOx measurement results shows that there is a good linear relationship between the two.

Pulse, blood oxygen, respiration and other cardiopulmonary monitoring parameters:

·Pulse frequency monitoring within the range of 90 to 900 BPM (beat per minute, BPM)

·Monitoring range of blood oxygen saturation: 0% to 100% arterial blood oxygen saturation;

·Blood oxygen saturation monitoring error:<1.5% across the entire monitoring range;

·Blood oxygen saturation monitoring response time: Real time reporting of arterial blood oxygen saturation, screen refresh 0.72 seconds after each heartbeat;

·Respiratory rate monitoring range: 25 to 450 times per minute;

·Monitoring reaction time: The respiratory rate is reported to the user every 1.7 seconds, and the mobile report value is the average of 10 breaths;

·Non traumatic monitoring of pulse filling to estimate changes in blood flow;

·Pulse monitoring range: microvessels with an inner diameter of 0 to 800 micrometers;

·Monitoring error:<2.4% across the entire monitoring range;

·Monitoring reaction time: Pulse filling degree is reported to the user in real-time. After each heartbeat, the screen refreshes 0.72 seconds to display all measured pulse filling degrees;

·Non traumatic monitoring of changes in animal respiratory amplitude;

·Respiratory amplitude monitoring range: 25 to 450 times per minute;

·Respiratory amplitude monitoring response time: The respiratory rate is reported to the user every 1.7 seconds, and the value of the mobile report is the average of 10 breaths;

Blood oxygen respiration data collector:

8-channel data collector

Pulse, blood oxygen, and respiratory data measurement can be performed on 1-8 mice

Analog signal output module:

Paired with an analog signal output module for real-time output of analog heartbeats

Multiple clock test probes are available for selection:

According to the needs, the neck probe used when the mouse is awake, the foot probe used when under anesthesia, and the thigh probe can be selected

Measurement software:

Real time display of monitoring data, with diagnostic mode and quotation function, data can be stored in Text or Windaq format

The device is conducting long-term and continuous data collection on conscious and active rats

Yuyan Instrument is owned by STARR Corporation in the United StatesAuthorized Chinese agentMouseox from Starr Corporation in the United States is a monitor specifically designed for mice and rats, capable of measuring parameters such as pulse oximetry, respiration, heart rate, pulse amplitude, respiratory amplitude, and body temperature. Please call us for more information!

· Calibration and Validation of the MouseOx ® Small-Animal Pulse Oximeter
Kingman P. Strohl* MD, David Baekey* PhD, Susan Dase** MS and Bernie Hete** PhD.
*Department of Pulmonary and Critical Care Medicine, Case Western Reserve University
**Department of Engineering, STARR Life Sciences Corp.

· Transfusion-related Acute Lung Injury
Chelsea A. Sheppard, MDa, Lennart E. Lo¨ gdberg, MD, PhDa, James C. Zimring, MD, PhDa, Christopher D. Hillyer, MDb,
aDepartment of Pathology and Laboratory Medicine, Room D-655, Emory University School of Medicine, 1364 Clifton Road, NE, Atlanta, GA 30322, USA
bDepartment of Pathology and Laboratory Medicine, Transfusion Medicine Program, Room D-655, Emory University Hospital, 1364 Clifton Road, NE, Atlanta, GA 30322, USAHEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA

· Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
Adam T. Boutin,1 Alexander Weidemann,1 Zhenxing Fu,5 Lernik Mesropian,1
Katarina Gradin,2 Colin Jamora,1 Michael Wiesener,3 Kai-Uwe Eckardt,3 Cameron J. Koch,4 Lesley G. Ellies,5
Gabriel Haddad,5 Volker H. Haase,4 M. Celeste Simon,4 Lorenz Poellinger,2 Frank L. Powell,5 and Randall S. Johnson1
1Molecular Biology Section, Division of Biological Sciences, UC San Diego, La Jolla, CA 92093, USA
2Karolinska Institute, Stockholm S-17177, Sweden
3University of Erlangen, Erlangen D-91054, Germany
4University of Pennsylvania Medical School, Philadelphia, PA 19104, USA
5Departments of Medicine, Pediatrics, and Pathology, UC San Diego School of Medicine, La Jolla 92093 CA, USA

· Age-related cardiac muscle sarcopenia: Combining experimental
and mathematical modeling to identify mechanisms
Jing Lin a,b, Elizabeth F. Lopez a,c, Yufang Jin f, Holly Van Remmen d,e, Terry Bauch a, Hai-Chao Han g, Merry L. Lindsey a, b,d,e
aDivision of Cardiology, Department of Medicine, The University of Texas Health Science Center at San Antonio (UTHSCSA),
7703 Floyd Curl Dr., MC-7872, San Antonio, TX 78229, USA
bThe Janey Briscoe Center of Excellence in Cardiovascular Research, UTHSCSA, USA
cJohn Jay Science and Engineering Academy, UTHSCSA, USA
dThe Barshop Institute for Longevity and Aging Studies, UTHSCSA, USA
eDepartment of Cellular and Structural Biology, UTHSCSA, USA
fDepartment of Electrical Engineering, UTSA, USA
gDepartment of Mechanical Engineering, UTSA, USA

· Post infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection
Ian C. Davis1, Eduardo R. Lazarowski2, Fu-Ping Chen3, Judy M. Hickman-Davis1, Wayne M. Sullender3,4, and Sadis Matalon1,4,5
1 Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
2 Department of Medicine, UNC, Chapel Hill, NC, USA
3 Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
4 Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
5 Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL 35233, USA

For more literature information, please call us for consultation.

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